small block, big block yada yada. most if built correctly with quality parts will make great power and last. for what you want to do is not impossible, it's just how deep is your pocket?
a friend of mine is running 8.60 in the quarter mile with a twin turbo 3.8 Grand National. then he turns the boost down and drive it home from the track. 110 miles each way. so it can be done.
just my 2cents
thanh